Journal
Clinical perspectives on therapeutic plasma exchange, longevity medicine, and the science of healthy aging — from Dr. Allen P. Green.
Latest Posts

What Joe Rogan Got Right About Plasmapheresis — And What to Know Before You Pick Up the Phone
Joe Rogan posted about receiving plasmapheresis. Here are the clinical answers to the questions everyone is asking — from a physician who supervises TPE every week.
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Why Plasma Exchange Should Come Before Stem Cell, Exosome, or PRP Therapy
If you're investing in stem cell therapy, exosomes, or PRP, the environment those therapies enter matters as much as the therapies themselves. Here's the clinical case for sequencing TPE first.
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Is the Albumin Used in Plasma Exchange Safe? A Physician Explains How It's Made
One of the most common questions I receive from patients concerns the 5% albumin we use as replacement fluid during therapeutic plasma exchange. Being a human-derived product raises several questions. Here is what you need to know.
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If Plasma Exchange Works, Why Isn't Your Doctor Recommending It?
The AMBAR trial showed effect sizes of 52–71% in slowing Alzheimer's progression — larger than any FDA-approved drug, with a fraction of the side effects. So why haven't you heard about it from your neurologist?
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What the Goop Article Gets Right About Plasma Exchange — And What to Know Before You Call
Gwyneth Paltrow's recent piece on therapeutic plasma exchange put a legitimate medical procedure in front of millions of readers. As a physician who has performed over 500 TPE procedures, here's the clinical context worth understanding before you book a session.
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Why I Built My Career Around Therapeutic Plasma Exchange
How following the science of aging in blood led me to Dr. Dobri Kiprov and Global Apheresis—and why I chose to treat patients rather than wait for academia to catch up.
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The Biomarker Question: How Do We Measure Success with Therapeutic Plasma Exchange?
Beyond biological clocks and blood panels — a physician's guide to tracking what therapeutic plasma exchange actually changes, and why your lived experience may be the most important biomarker of all.
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AMBAR Part 3: Plasma Exchange Slows Alzheimer's Decline Regardless of Amyloid Status
The finding that changed how we think about what plasma exchange is actually doing — and why it matters for everyone, not just Alzheimer's patients.
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AMBAR Part 2: Independent Validation and Comparison to FDA-Approved Drugs
In Part 1, we explored the AMBAR study design and clinical results. Now we examine the mechanistic evidence, independent validation from Argentina, and how plasma exchange compares to FDA-approved monoclonal antibodies.
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The AMBAR Study: Part 1 — Understanding Plasma Exchange and Key Results
The AMBAR trial showed effect sizes of 52–71% in slowing Alzheimer's progression — and most neurologists have never heard of it. Here's what the data actually shows.
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The Blood Revolution: How Scientists Discovered That Aging Lives in Your Blood — And How to Reverse It
How two decades of parabiosis research led to a medical procedure that can reduce biological age — and what it means for the future of medicine.
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The Hidden Risk of Weight Loss: How Forever Chemicals Get Released During Fat Loss
Why losing weight might temporarily increase your toxin exposure — and the therapeutic solution that can help
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The Jersey PFAS Crisis: Why Government-Recommended "Bloodletting" Isn't Enough
How a decades-long contamination cover-up in the English Channel became a case study in the gap between government health recommendations and the best available medicine.
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TPE for Detoxification: The Science-Based Solution for Forever Chemicals and Environmental Toxins
How therapeutic plasma exchange directly removes PFAS, heavy metals, and synthetic chemicals that conventional detox approaches cannot reach.
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Therapeutic Plasma Exchange for Healthcare Providers: A Clinical Implementation Guide
What it actually takes to bring therapeutic plasma exchange into an outpatient practice — equipment, staffing, costs, and what experienced clinics have learned.
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Therapeutic Plasma Exchange: Transforming Health and Longevity
A physician's overview of what TPE is, what the evidence shows, and the four areas where it's changing medicine.
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Video from Global Apheresis, where Dr. Green practices.
Videos produced by Global Apheresis. Dr. Allen P. Green serves as Associate Medical Director.
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